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Case raises concern that sotatercept may be associated with serious and recurrent gastrointestinal bleeding

Sotatercept is an investigational medicine that has shown positive results for treating adults with pulmonary arterial hypertension. In the phase 2 PULSAR and phase 3 STELLAR trials, epistaxis, skin telangiectasias, and thrombocytopenia were more frequent among those taking sotatercept compared with placebo. To date, sotatercept has not been associated with recurrent gastrointestinal bleeding.

Source: Medical Xpress

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  • American Society for Gastrointestinal Endoscopy
  • American College of Gastroenterology
  • American Gastroenterological Association
  • American Association for the Study of Liver Diseases